Antispasmodic Derivatives of Dialkylphenylacetic Acids.
نویسندگان
چکیده
منابع مشابه
Synthesis of N-substituted piperazinyl carbamoyl and acetyl derivatives of tetrahydropapaverine: potent antispasmodic agents.
The synthesis and structure-activity-relationship (SAR) for a series of N-substituted piperazinyl carbamoyl 7-15 and piperazinyl acetyl 18-26 derivatives of tetrahydropapaverine have been carried out. The general synthetic methods of carbamoyl tetrahydropapaverine analogues involve N-substituted piperazines and carbamoyl imidazole tetrahydropapaverine as starting materials. Another route for sy...
متن کاملAntispasmodic Effects of Some N-substituted 2- Methyl Imidazole Derivatives on Guinea Pig Ileum
A series of novel N-substituted 2-methyl imidazole derivatives have been synthesized, and their in vitro antispasmodic activity was assessed on contractions of isolated guinea pig ileum, induced by acetylcholine (5× 10M to 1× 10M), and compared with the effect of atropine. All the prototypes were synthesized and confirmed by their FTIR, HNMR, MASS and elemental spectral data. Antispasmodic acti...
متن کاملCHIRAL SEPARATIONS Amino Acids and Derivatives See III /AMINO ACIDS AND DERIVATIVES: CHIRAL SEPARATIONS
use by the OPCW inspectorate. Use of GC with one or more spectrometric technique such as mass spectrometry is required to conRrm the presence of chemical warfare agents. For this reason many analyses are carried out by GC-MS under electron impact or chemical ionization conditions. For analyses involving low levels of chemical warfare agents in the presence of high levels of interfering chemical...
متن کاملMicrobial fatty acids and derivatives in biotechnology
Food lipids http://www.stu.edu.vn/uploads/documents/ 030509-215944.pdf Some food lipids are obtained from microbes. This book offers a comprehensive account of food lipid chemistry and biotechnology. Antimicrobial lipids on skin http://www.jlr.org/cgi/reprint/49/1/4 This web article describes the surprising finding that a monounsaturated C16 fatty acid is the most effective antimicrobial agent ...
متن کاملAmino Acids and Derivatives: Chiral Separations
particularly because with TLC various phase systems can be checked at the same time without expensive apparatus. TLC will continue to serve as a useful method for daily routine control analyses to identify and determine the purity of a variety of compounds, including enantiomers, with ease and speed, and can be readily modiRed for new situations. A wide choice for separation conditions will alw...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1952
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.06-0615